Searchable abstracts of presentations at key conferences on calcified tissues

ba0005p31 | Bone biomechanics and quality | ECTS2016

Site specific bone loss induced by spaceflight in mice: a multiscale evaluation of trabecular and cortical structure and quality

Gerbaix Maude , Gnyubkin Vasily , Delphine Farlay , Helene Follet , Patrick Ammann , Cecile Olivier , Francoise Peyrin , Norbert Laroche , Boris Shenkman , Guillemette Gauquelin-Koch , Laurence Vico

Intrinsic quality, micro and nano structure of bone after 1 month of spaceflight and during 1 week of recovery had never been investigated. The aim was to explore these properties in appendicular and axial skeleton of mature mice.Ten C57/Bl6 male mice flew on the 30-day space Russian BION-M1 high-orbit satellite mission (Biomedical Ethics Commission of IBMP, n°319). Five were euthanized 12 h after landing, the others 8 days later. A ground control g...